AB569, a Novel, Topical Bactericidal Gel Formulation, Kills Pseudomonas aeruginosa and Promotes Wound Healing in a Murine Model of Burn Wound Infection

Authors Amanda Barry, Warunya Panmanee, Daniel J. Hassett Details Published in Infection and Immunity, Volume 89, Number 11 – 15 October 2021Read the full publication at ASM Journals or at download the PDF Abstract Cutaneous thermal injuries from burns/explosives are a major cause of morbidity and mortality and represent a monumental burden on our current … Read more

AB569, a non-toxic combination of acidified nitrite and EDTA, is effective at killing the notorious Iraq Afghanistan combat wound pathogens, multi-drug resistant Acinetobacter baumannii and Acinetobacter spp

Authors Amy L Bogue, Warunya Panmanee, Cameron T McDaniel, Joel E Mortensen, Edwin Kamau, Luis A Actis, Jay A Johannigman, Michael J Schurr, Latha Satish, Nalinikanth Kotagiri, Daniel J Hassett Details Published in PloS One, March 3, 2021, Read the full publication at PloS One or at PMC NIH Abstract Multi-drug resistant (MDR) Acinetobacter baumannii … Read more

A Novel Bactericidal Drug Effective Against Gram-Positive and Gram-Negative Pathogenic Bacteria: Easy as AB569

Authors Daniel J. Hassett and Thomas J. Meyer Details Published in DNA and Cell Biology. September 4, 2020 – 1473-1477. Read the abstract, or access the journal here Abstract Global antibiotic resistance, driven by intensive antibiotic exposure/abuse, constitutes a serious challenge to all health care, particularly in an era when new antimicrobial development has slowed to a … Read more

AB569, a nontoxic chemical tandem that kills major human pathogenic bacteria

Authors Cameron T. McDaniel, Warunya Panmanee, Geoffrey L. Winsor, Erin Gill, Claire Bertelli, Michael J. Schurr, Prateek Dongare, Andrew T. Paul, Seung-Hyun B. Ko, Gee W. Lau, Nupur Dasgupta, Amy L. Bogue, William E. Miller, Joel E. Mortensen, David B. Haslam, Phillip Dexheimer, Daniel A. Muruve, Bruce J. Aronow, Malcolm D. E. Forbes, Marek Danilczuk, … Read more

A Putative ABC Transporter Permease is Necessary For Resistance to Acidified Nitrite and EDTA in Pseudomonas aeruginosa Under Aerobic, Anaerobic, Planktonic or Biofilm Conditions

Authors Cameron McDaniel, Warunya Panmanee, Shengchang Su, Renuka Kapoor, Kevin Cox, Andrew Paul, Gee Lau, Seung-Hyun Ko, Joel Mortensen, Joseph S. Lam, Daniel Muruve and Daniel Hassett Details Published in Frontiers in Microbiology, Front. Microbiol., 01 April 2016 | doi: 10.3389/fmicb.2016.00291Read the full journal article here Pseudomonas aeruginosa (PA) is an important airway pathogen of … Read more